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Hope Blooms For Cancer Patients

Hope Blooms: Indian Doctor Declared Cancer-Free After Receiving Indigenous CAR-T Cell Therapy For the hope for cancer patients across India, Dr. (Col) V.K. Gupta, a Delhi-based gastroenterologist, has become the first person declared free of cancer cells after receiving India's indigenously developed CAR-T cell therapy. This groundbreaking treatment, recently approved for commercial use, marks a significant leap forward in the country's fight against the disease. What is CAR-T Cell Therapy? CAR-T, short for Chimeric Antigen Receptor T-Cell therapy, is a revolutionary approach that utilizes a patient's own immune system to combat cancer. T cells, a type of white blood cell, are extracted from the patient, genetically modified to recognize and attack specific cancer cells, and then reinfused back into the body. This personalized army of immune cells then launches a targeted assault on the tumor, offering a powerful and potentially curative option for certain types of cancer. India's Indigenous Success The CAR-T therapy received by Dr. Gupta was developed by ImmunoACT, a company incubated at the prestigious Indian Institute of Technology Bombay (IITB) in collaboration with Tata Memorial Hospital. This "homegrown" solution holds immense significance as it makes this potentially life-saving treatment **more accessible and affordable** for Indian patients. Traditionally, CAR-T therapy has been associated with exorbitant costs, often exceeding millions of rupees. However, the Indian version is significantly cheaper, offering hope to a wider population battling the disease. A Spark of Hope Dr. Gupta's case, though requiring further observation to confirm long-term remission, serves as a powerful testament to the potential of this indigenous therapy. It signifies the remarkable advancements being made in India's medical field and paves the way for more patients to benefit from this potentially life-saving treatment. Beyond Gupta's Case The success of this indigenous CAR-T therapy holds wider implications for the future of cancer treatment in India. It underscores the country's growing scientific prowess and its commitment to developing affordable and accessible healthcare solutions. This advancement can potentially: Reduce the financial burden on cancer patients and their families. Increase access to advanced treatment options for a wider population. Fuel further research and development in the field of immunotherapy in India. While Dr. Gupta's case is a cause for celebration, it's crucial to remember that CAR-T therapy is still in its early stages. Continued research and clinical trials are necessary to refine the technology, improve its efficacy, and expand its reach. Nonetheless, this breakthrough marks a significant step forward in India's fight against cancer, offering a glimmer of hope for countless patients and their loved ones. Links to News Articles and Research Papers: India Today: https://www.indiatoday.in/health/story/patient-declared-cancer-free-using-indian-made-car-t-cell-therapy-2499650-2024-02-09 Max Healthcare: https://health.economictimes.indiatimes.com/news/hospitals/max-healthcare-launches-car-t-cell-therapy-in-collaboration-with-immunoact/105756241 ImmunoACT Website: https://www.immunoact.com/ The New England Journal of Medicine: https://pubmed.ncbi.nlm.nih.gov/29226797/ Interviews: Interviewing Dr. Gupta himself would be fantastic, but if that's not possible, consider reaching out to: Doctors involved in his treatment at Tata Memorial Hospital. Experts in CAR-T therapy from other institutions in India. Representatives from ImmunoACT or IITB for insights into the development of the therapy. Availability and Cost: The therapy, NexCAR19, is currently available in over 30 hospitals in 10+ Indian cities. Check ImmunoACT's website for details on specific hospitals and eligibility criteria. While more affordable than international options, the exact cost might vary depending on the hospital and individual case. Mentioning a range (e.g., significantly cheaper than $480,000 abroad) would be helpful.

The Miracle Drug For The Treatment Of Colorectal Cancer

A tiny (18 patient) group of colorectal patients recently underwent a medical miracle when their illness fully disappeared following experimental therapy administered by a team of experts at Memorial Sloan Kettering Cancer Center in New York. The trial's outcome was unexpected because every patient was entirely cured, without exception. Some specialists in the field of cancer research claim that these ground-breaking findings are unexpected [8]. These individuals had life-altering surgery that might affect bowel, urinary, and sexual functions, as well as treatments including chemotherapy and radiation.  Dr. Diaz's 2017 clinical trial design served as the study's primary source of inspiration. 86 people with metastatic cancer that had spread throughout their bodies were included. However, a gene mutation present in every tumour rendered cells incapable of repairing DNA damage. 4% of cancer patients had these mutations. Patients in that study received pembrolizumab, a checkpoint inhibitor from Merck, for up to two years. Tumors decreased in size or stabilised in around one-third to one-half of the patients, prolonging their survival. 10% of participants who took part in the trial had their tumours removed. According to the researchers, the experiment has to be repeated in a much bigger sample because the current study only examined people whose tumours had a certain genetic profile. However, they think that seeing complete remission in all of the individuals who were investigated is a very encouraging early indicator. Read complete article at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433597/

How Many Countries Have Visa-free Or Visa-on-arrival Entry In India?

There are 60 countries that have visa-free or visa-on-arrival entry to India as of August 4, 2023. Passport holder of these countries are eligible for visa on arrival or visa free entry in India. The list of countries is as follows: Antigua and Barbuda Argentina Bahamas Barbados Belize Bhutan Bolivia Brazil Brunei Cambodia Cape Verde Chile Colombia Cook Islands Dominica Fiji Gambia Grenada Guyana Haiti Hong Kong (SAR China) Indonesia Iran Israel Jamaica Kazakhstan Kiribati Laos Macao (SAR China) Maldives Malaysia Mauritius Mexico Micronesia Mongolia Montserrat Myanmar Namibia Nauru Nepal Nicaragua Niue Oman Palau Paraguay Peru Philippines Qatar Saint Kitts and Nevis Saint Lucia Saint Vincent and the Grenadines Samoa Senegal Serbia Seychelles Singapore Solomon Islands South Africa South Korea Sri Lanka Suriname Swaziland Taiwan Tajikistan Tanzania Thailand Timor-Leste Togo Tonga Trinidad and Tobago Tuvalu Uganda Ukraine United Arab Emirates Uruguay Uzbekistan Vanuatu Venezuela Zambia Zimbabwe Citizens of these countries can either enter India without a visa or obtain a visa on arrival at a designated port of entry. The validity of the visa-on-arrival and the length of stay will vary depending on the nationality of the traveler. It is important to note that the visa requirements for India can change at any time, so it is always best to check with the Indian embassy or consulate in your home country before you travel to confirm the latest requirements.

How Many Types Of Visa Are There And What Is The Difference?

Types of Indian Visa There are 24 types of visas for India, each with its own specific purpose and requirements. The different types of visas can be broadly classified into the following categories: Entry visas: Entry visas are issued to foreigners who are not Indian citizens or Overseas Citizens of India (OCIs) and who wish to visit India for any purpose other than tourism, business, or employment. Entry visas are typically issued for single or multiple entry and can be valid for up to five years. Business visas: Business visas are issued to foreigners who are not Indian citizens or OCIs and who wish to visit India for business purposes, such as attending meetings, negotiating contracts, or setting up a business. Business visas are typically issued for single or multiple entry and can be valid for up to five years. Employment visas: Employment visas are issued to foreigners who are not Indian citizens or OCIs and who have been offered a job in India. Employment visas are typically issued for single or multiple entry and can be valid for up to five years. Student visas: Student visas are issued to foreigners who are not Indian citizens or OCIs and who wish to study in India. Student visas are typically issued for single or multiple entry and can be valid for up to five years. Medical visas: Medical visas are issued to foreigners who are not Indian citizens or OCIs and who need to travel to India for medical treatment. Medical visas are typically issued for single or multiple entry and can be valid for up to six months. Tourist visas: Tourist visas are issued to foreigners who are not Indian citizens or OCIs and who wish to visit India for tourism purposes. Tourist visas are typically issued for single or double entry and can be valid for up to 60 days. he required details and documents for the different types of visas for India vary depending on the type of visa. However, most types of visas require the following documentation: A valid passport with at least six months validity beyond the intended date of departure from India. A completed visa application form. A passport-sized photo. Proof of onward travel (e.g., a flight ticket or hotel reservation). Evidence of financial means to support themselves during their stay. In addition to the above, some types of visas may also require the following documentation: Entry visa: A letter of invitation from a company or individual in India. Business visa: A business letter from your employer or a letter of invitation from a company in India. Employment visa: A job offer letter from an employer in India and a copy of your employment contract. Student visa: A letter of acceptance from a school or university in India and proof of financial support. Medical visa: A medical certificate from a doctor stating the need for treatment and a letter from the hospital or clinic where the treatment will be received. Tourist visa: Proof of accommodation and evidence of financial means to support themselves during their stay. Required Documents for an Indian Visa in these categories  It is important to note that the specific requirements for each type of visa may vary. It is always best to check with the Indian embassy or consulate in your home country to confirm the latest requirements. Here are some additional details that may be required for certain types of visas: Entry visa: The purpose of your visit to India. The dates of your intended stay in India. The addresses of the places where you will be staying in India. Business visa: The name and address of the company you will be visiting in India. The purpose of your business visit. The dates of your intended stay in India. Employment visa: The name and address of your employer in India. The nature of your job. The salary you will be earning. The dates of your intended stay in India. Student visa: The name and address of the school or university you will be attending in India. The course of study you will be pursuing. The duration of your studies. Proof of financial support. Medical visa: The name and address of the hospital or clinic where you will be receiving treatment in India. The nature of your medical condition. The estimated cost of your treatment. Tourist visa: The itinerary for your trip to India. Proof of accommodation in India. Evidence of financial means to support yourself during your stay in India. Once you have gathered all of the required documents, you can submit your visa application to the Indian embassy or consulate in your home country. The processing time for visa applications can vary, so it is important to apply well in advance of your planned trip to India. For more and better details please contact to Indian Embassy in your country.

Has The Indian Government Started Issuing Visas Again After The Pandemic?

Has the Indian Government started issuing visas again after the pandemic? As many as 19 Bangladeshis travelled to India through Benapole port on medical visas with the approval of the house Ministry’s security services division on Wednesday, taking the entire number to 45 within the last three days. Meanwhile, Bangladeshis coming back from India are being kept in 14 days of mandatory institutional quarantine at different hotels in Jessore, Benapole and other areas at their expenses. The Bangladesh government imposed a ban on visits to and from India from April 26 to stop the spread of Covid-19, including a replacement variant of the deadly disease. A large number of Bangladeshis visit India on medical visas on a daily basis. Thanks to the travel ban, the treatment process of the many patients was disrupted tremendously. Patients handling complex diseases suffered the foremost . Dhiman Sarkar, a Bangladeshi who visited India on a medical visa, said: “My girl was affected by a posh disease. I visited India three months ago for her treatment. We were supposed to return within a month, but we couldn’t make it thanks to the travel ban, because the Covid situation deteriorated further.  “Now we've received clearance from the house Ministry, after seeking permission. But we had to satisfy various conditions, including the arrangement of Covid-19 negative certificates within 72 hours of testing,” he added. Also Read - Covid-19: Khulna division again sets record with 32 deaths during a day Jahanara Begum said: “I are visiting India for medical treatment, risking my life amid this pandemic. I wouldn’t need to , if treatment facilities in our country were improved. According to immigration sources, the govt has decided to grant a conditional travel permit to India on humanitarian grounds after two months of the newest ban. The Indian government has responded positively to the initiative. Benapole Immigration OC Ahsan Habib said: “Patients affected by complex diseases have the chance to go to India on medical visas with conditional travel permits from the house Ministry. Bangladeshis coming back from India are returning with special clearance from the Bangladesh embassy in India.” Around 5,562 Bangladeshis have returned to the country from India within the last 56 days. During this era , 45 Bangladeshis and 1,000 Indians visited India from Bangladesh, he added. The Indian government had suspended all existing visas apart from diplomatic, official, UN, world organization , employment and project visas on March 13, 2020. After several months, the suspension was eased because the Covid-19 situation developed in both counties. The ongoing travel ban was imposed on April 26, 2021, following a huge surge in Covid-19 cases within the region.

Pig Kidney Transplant Successfully Works In Human For Two Months

In a groundbreaking medical experiment, a pig kidney was successfully transplanted into a human and functioned normally for two months. This is the longest a genetically modified pig kidney has ever functioned inside a human, albeit a deceased one. The experiment, conducted by surgeons at NYU Langone Health, was a major step forward in the field of xenotransplantation, which is the transplantation of organs from animals to humans. Xenotransplantation has been a goal of medical science for decades, as it could potentially help to alleviate the shortage of human organs available for transplant. However, xenotransplantation has been plagued by challenges, including the human immune system's rejection of foreign tissue. The NYU Langone Health team addressed this challenge by using a genetically modified pig kidney. The kidney was modified to remove genes that trigger an immune response in humans, and to add genes that make the kidney more compatible with the human body. The kidney was transplanted into a brain-dead man who had agreed to donate his body for the experiment. The kidney functioned normally for two months, producing urine and filtering waste products from the blood. The researchers also found that the pig kidney responded to human hormones and excreted antibiotics in the same way as a human kidney. While the experiment was successful, it is important to note that it was conducted in a deceased person. The next step is to test pig kidneys in living humans, which is more challenging due to the risk of organ rejection. However, the results of the NYU Langone Health experiment are a promising sign that xenotransplantation may one day be a viable option for patients with end-stage organ disease.