A tiny (18 patient) group of colorectal patients recently underwent a medical miracle when their illness fully disappeared following experimental therapy administered by a team of experts at Memorial Sloan Kettering Cancer Center in New York. The trial's outcome was unexpected because every patient was entirely cured, without exception. Some specialists in the field of cancer research claim that these ground-breaking findings are unexpected [8]. These individuals had life-altering surgery that might affect bowel, urinary, and sexual functions, as well as treatments including chemotherapy and radiation. 

Dr. Diaz's 2017 clinical trial design served as the study's primary source of inspiration. 86 people with metastatic cancer that had spread throughout their bodies were included. However, a gene mutation present in every tumour rendered cells incapable of repairing DNA damage. 4% of cancer patients had these mutations. Patients in that study received pembrolizumab, a checkpoint inhibitor from Merck, for up to two years. Tumors decreased in size or stabilised in around one-third to one-half of the patients, prolonging their survival. 10% of participants who took part in the trial had their tumours removed. According to the researchers, the experiment has to be repeated in a much bigger sample because the current study only examined people whose tumours had a certain genetic profile. However, they think that seeing complete remission in all of the individuals who were investigated is a very encouraging early indicator.

Read complete article at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433597/